Mineharu Lab
Neurosurgery / DX in Healthcare and Medicine
The Mineharu Lab at Kyoto University conducts multifaceted research that integrates medical AI, induced pluripotent stem (iPS) cell technology, and data science, grounded in advanced clinical expertise in neurosurgery.
By bridging the boundaries between medicine and technology from elucidating the mechanisms of intractable diseases to implementing AI-based disease prediction applications in clinical practice we aim to provide care tailored to the needs of each individual patient.
RESEARCH THEME
AMED PROJECT
2023 ～ 2025
Clarification of optimal condition to improve health behavior adherence using personalized disease prevention support App
Drawing on three years of research, we established a next-generation preventive healthcare platform in which AI promotes behavior change tailored to each individual’s characteristics.
By integrating medical evidence with data science, the platform enables interventions optimized to each user’s risk profile. Designed to prevent the onset of diseases, including cerebrovascular disorders, it provides a pioneering model for practical, real-world digital healthcare.
PUBLICATION
- Molecular and clinical features of a Japanese medulloblastoma cohort: Subgroup‐specific prognostic stratification using economical/accessible diagnostic methods
Kohichi Go, Asako Katsuma, Ema Yoshioka, Tomoko Shofuda, Kohei Fukuoka, Koichi Ichimura, Yuko Matsushita, Yohei Mineharu, Yasuhide Makino, Takeshi Kawauchi …
Brain Pathology 2026 - A deep state-space analysis framework for cancer patient latent state estimation and classification from EHR time-series data
Yuji Okamoto, Aya Nakamura, Ryosuke Kojima, Eiichiro Uchino, Yohei Mineharu, Yohei Harada, Mayumi Kamada, Minoru Sakuragi, Manabu Muto, Motoko Yanagita …
PLOS One 2026 - Peripheral blood GATA2 expression impacts RNF213 mutation penetrance and clinical severity in moyamoya disease
Yohei Mineharu, Takahiko Kamata, Mei Tomoto, Noriaki Sato, Yoshinori Tamada, Takeshi Funaki, Yuki Oichi, Kouji H Harada, Akio Koizumi, Tetsuaki Kimura …
Stroke and Vascular Neurology 2025
FOR STUDENTS / RECRUIT
Our laboratory is an independent research group at the intersection of clinical neurosurgery and cutting-edge data science. With medical AI, iPS cell research, and advanced clinical research as our three core pillars, we welcome students and early-career researchers who share our vision.
We welcome people from all academic backgrounds, including medicine and informatics. We are looking for individuals with the passion to explore uncharted territory and make a meaningful contribution to society.