Mineharu Lab
Neurosurgery / Health and Medical DX
Building on advanced clinical expertise in neurosurgery, Mineharu Lab conducts multidisciplinary research that integrates medical AI, iPS cells, and data science.
From elucidating the pathogenesis of intractable diseases to the societal implementation of AI-powered disease prediction apps, we aim to provide optimal medical care for each and every patient by transcending the boundaries between medicine and technology.
RESEARCH THEME
AMED PROJECT
2023 ～ 2025
Development of a personalized disease prevention support app
By synthesizing three years of research findings, we have established a next-generation preventive healthcare platform that uses AI to encourage behavioral changes tailored to individual characteristics.
By integrating medical evidence with data science, we have developed interventions optimized for each user’s specific risk profile. Aiming to prevent the onset of diseases such as cerebrovascular disorders, we have built a model that serves as a pioneer in practical digital healthcare.
PUBLICATION
- Molecular and clinical features of a Japanese medulloblastoma cohort: Subgroup‐specific prognostic stratification using economical/accessible diagnostic methods
Kohichi Go, Asako Katsuma, Ema Yoshioka, Tomoko Shofuda, Kohei Fukuoka, Koichi Ichimura, Yuko Matsushita, Yohei Mineharu, Yasuhide Makino, Takeshi Kawauchi …
Brain Pathology 2026 - A deep state-space analysis framework for cancer patient latent state estimation and classification from EHR time-series data
Yuji Okamoto, Aya Nakamura, Ryosuke Kojima, Eiichiro Uchino, Yohei Mineharu, Yohei Harada, Mayumi Kamada, Minoru Sakuragi, Manabu Muto, Motoko Yanagita …
PLOS One 2026 - Peripheral blood GATA2 expression impacts RNF213 mutation penetrance and clinical severity in moyamoya disease
Yohei Mineharu, Takahiko Kamata, Mei Tomoto, Noriaki Sato, Yoshinori Tamada, Takeshi Funaki, Yuki Oichi, Kouji H Harada, Akio Koizumi, Tetsuaki Kimura …
Stroke and Vascular Neurology 2025
FOR STUDENTS / RECRUIT
Our laboratory is an independent research group situated at the intersection of neurosurgery and cutting-edge data science. We welcome like-minded students and early-career researchers to join us as we focus on three key areas: medical AI, iPS cells, and advanced clinical research.
We welcome applicants from all fields, including medicine and computer science. We are looking for individuals with a passion for exploring uncharted territory and contributing to society.